Open Access Lab

There are two instruments available in the Open Access Laboratory: an Agilent 6220 ESI-TOF high resolution mass spectrometer with HPLC, and a Bruker UTX MALDI-TOF/TOF. Currently, only the Bruker MALDI-TOF/TOF is available to outside users. Please contact us at (617) 384-9585 if you would like to be trained on the following instruments.  All reservations and billing is done through the SPINAL reservation system. Before requesting training, you have to provide a purchase order with sufficient funds to cover the training and short term anticipated use of our equipment. The hourly cost of usage of open access equipment is as follows:


Harvard Hourly Rate

  Academic/non-profit Hourly Rate     

 Corporate Hourly Rate 

Agilent ESI-TOF

$50 New




$100 $200

Agilent 1200 HPLC


*Training ESI-TOF  $165 NA NA
*Training MALDI-TOF and access $165 $290 $330

*Training charges are being introduced effective 12/1/2016. When requesting authorization to use an instrument, you will need to attend a 1 hour training course for either the Bruker Ultraflextreme MALDI-TOF or the ESI-TOF. The charges covers training, and initial authorization. Before training, you will provide your 33 digit code to Sunia so that you can be billed.

Staff-Run Services (all rates are per-Individual analysis)

Note: If  you are requesting that we run both positive and negative ion mode, this counts as two individual runs/analyses because it typically requires twice the time. In some cases we may employ polarity switching. However, this is not always recommended due to specific instrument limitations or compromise of sensitivity.


Harvard Rate

(per analysis/run)


(per analysis/run)


(per analysis/run)

















Quick Protein ID (using MALDI-TOF/TOF)




Untargeted Lipidomics LipidSearch based ID

for entire batch of samples





Bulk Rate for Researchers from Harvard University and Non-Profit Organizations

Please note that a high volume/bulk rate is now available for researchers from Harvard University and Non-Profit organizations to facilitate experiments that require the analysis of a large number of LC-MS samples.  Please check our policy and high volume rates.

How does the hourly charge work?

*Please note that certain custom analyses such as quantitation of small molecules require methods development.  The HPLC or GC methods development charge is $60 per hour for Harvard, $105 per hour non-profit, $120 per hour for Corporate users.  Please check out our guidelines for calculating an estimate of what the methods development charge would be depending on the individual compound, and inherent difficulty in the methods development process.

Harvard and Non-Harvard Status

Your Harvard/non-Harvard affiliation status is determined solely by whether you have a 33-digit internal billing code.  If this code is not available, you will be charged the non-Harvard rate based on the university overhead rate and ease of billing considerations.  In the absence of an internal billing code, you will be considered an outside user since this indicates that an overhead has not been paid to Harvard FAS which subsidizes our internal costs. 

Preparing a Purchase Order for Outside Samples New-07/24/15

All outside users must submit purchase orders (PO) addressed to Harvard University.  Here is our W-9 tax document to set us up as a vendor at your organization. We need the actual PO as a hardcopy, not just a number(.pdf preferable). POs with the incorrect address will not be accepted! Please note that a PO is a legal document which must have the correct address/be on the letterhead of the organization! We have recently migrated to the university's central Accounts Receivable. The new address to put on the purchase order is the following. Now the check is mailed to an address at the bank: P.O.Box 4999, Boston, MA and these instructions will be provided to you on the invoice you receive. However, strictly legally speaking, the Purchase Order needs to be made out to the address on the W9 of Harvard, which is:

Harvard University
1033 Massachusetts Ave
2nd Floor
Cambridge, MA 02138
The .pdf file of the purchase order must be up-loaded into our sample submission and tracking system (MiniLIMS) at the time of sample submission. Please call us at (617) 384-9585 if you have any questions about pricing.
DO NOT SHIP samples to the above address!  Ship your samples on dry ice if appropriate to the following address:

Small Molecule Mass Spectrometry
Northwest Laboratories, B243.10
52 Oxford St. 

Cambridge, MA 02138

(617) 384-9585