Services

We are a full-service mass spectrometry facility that provides fee-for-service analysis for a wide variety of applications.  In addition, we provide training and use of an LC-MS (ESI-TOF) and MALDI-TOF mass spectrometer and HPLCs on an open access (24/7) basis.

Fee-for-Service Analysis

This includes, accurate mass analysis of small molecules and proteins (average MW).   We also routinely perform quantitative measurements of small molecules on the triple quad mass spectrometer using LC-MS/MS and multiple reaction monitoring (MRM).  Other types of analyses include untargeted and targeted metabolomics measurements.  We have a new on-line sample submission system which can be used to submit samples and retrieve results.  To submit samples, first register as new users on our online sample submission and tracking system also known as MiniLIMS.  For step by step directions to registering and using MiniLIMS, please see link. Please contact Sunia at (617) 384-9585 to discuss your specific analysis needs.  We are happy to hear from you and consult on any questions related to mass spectrometry.  

Open Access Analysis

The facility operates an open access lab where individual researchers are able to use two mass spectrometers (ESI-TOF and MALDI-TOF) and one HPLC after some initial training by our staff.  The training process involves familiarization with the background and instruments, creation of a RC account and training in the use of SPINAL, our on-line reservation and billing system.  It is recommended that you start the registration process for SPINAL at least a week before intending to use the instrument.  This is necessary to get approval of billing codes and establishment of proper accounts.  For more information on how to get started on SPINAL, please see the step-by-step instructions.  To find out how to get started with training, contact Sunia Trauger strauger@fas.harvard.edu

  • Agilent ESI-TOF MS
  • Waters MALDI -TOF mass spectrometer (reflectron and linear modes)
  • Bruker Ultraflextreme MALDI-TOF/TOF
  • Agilent 1200 HPLC with a Diode Array Detector (DAD)

Sample Preparation Instructions

For specific information about sample preparation for your particular samples, please call us or email us. Here is some general information about sample preparation.

Rates

For information on our rates and billing policies, please go to our rates page. Our rates are uniform and consistent to comply with government funding agency auditing requirements.

Billing and Sample Submission Forms